Dr. Soheil Meshinchi is a physician scientist and a Full Member at the Fred Hutchinson Cancer Research Center, as well as Professor of Pediatrics at the University of Washington School of Medicine. With over 25 years of experience in AML biology, he chairs the COG Myeloid Disease Biology Committee and the NCI designated Hematopoietic Integrated Science Center (HM-ITSC) to help translate laboratory discoveries into clinical practice. He leads the novel target and biomarker discovery for the LLS Children’s Initiative and the Pediatric Acute Leukemia (PedAL) efforts. As the director of NCI TARGET AML initiative and the Target Pediatric AML (TpAML), , he has led multi-omic studies of over 3000 children and young adults; Studies including Whole Genome Sequencing, Transcriptome sequencing, miRNA sequencing, Methylation profiling as well as the ongoing long read RNA sequencing to fully define splice isoforms in normal and malignant hematopoiesis.